SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   ----------

                                  SCHEDULE 13G
                                 (RULE 13D-102)

 INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13D-1(B),(C)
         AND (D) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13D-2(B)
                               (AMENDMENT NO.__)1


                               AVI BIOPHARMA, INC.
                                (Name of Issuer)

                    Common Stock, par value $.0001 per share
                         (Title of Class of Securities)

                                    637184108
                                 (CUSIP Number)


                                 March 25, 2005
             (Date of Event Which Requires Filing of this Statement)

         Check the  appropriate box to designate the rule pursuant to which this
Schedule is filed.

         [ ] Rule 13d-1(b)

         [X] Rule 13d-1(c)

         [ ] Rule 13d-1(d)


-----------------------

              1 The  remainder  of this  cover  page  shall be filled  out for a
reporting person's initial filing on this form with respect to the subject class
of securities,  and for any subsequent  amendment  containing  information which
would alter the disclosures provided in a prior cover page.

              The information required in the remainder of this cover page shall
not be deemed to be "filed"  for the  purpose  of  Section 18 of the  Securities
Exchange Act of 1934 or otherwise  subject to the liabilities of that section of
the Act but shall be subject to all other  provisions of the Act  (however,  SEE
the NOTES).









CUSIP NO. 637184108                   13G                      PAGE 2 OF 6 PAGES
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1.       NAME OF REPORTING PERSONS
         I.R.S.  IDENTIFICATION  NOS. OF ABOVE PERSONS (ENTITIES ONLY)
         George W. Haywood
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2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP * (a) [ ]
                                                            (b) [ ]
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3.       SEC USE ONLY

--------------------------------------------------------------------------------

4.       CITIZENSHIP OR PLACE OF ORGANIZATION
         U.S.A

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  NUMBER OF                5.      SOLE VOTING POWER               3,071,000
  SHARES                   -----------------------------------------------------
  BENEFICIALLY             6.      SHARED VOTING POWER                50,000 (1)
  OWNED BY                 -----------------------------------------------------
  EACH                     7.      SOLE DISPOSITIVE POWER          3,071,000
  REPORTING                -----------------------------------------------------
  PERSON WITH              8.      SHARED DISPOSITIVE POWER           50,000 (1)

--------------------------------------------------------------------------------
 9.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         3,121,000
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 10.     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
         []
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11.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
         7.1%
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12.      TYPE OF REPORTING PERSON *
         IN
--------------------------------------------------------------------------------

(1) Consists of shares owned by spouse.

         *    SEE INSTRUCTIONS BEFORE FILLING OUT.

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ITEM 1(A).        NAME OF ISSUER:

                  Avi Biopharma, Inc.

ITEM 1(B).        ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:

                  One SW Columbia Street, Suite 1105, Portland, Oregon 97258

ITEM 2(A).        NAME OF PERSON FILING:

                  George W. Haywood

ITEM 2(B).        ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:

                  c/o Cronin & Vris, LLP, 380 Madison Avenue, 24th Floor,
                  New York, New York 10017

ITEM 2(C).        CITIZENSHIP:

                  U.S.A

ITEM 2(D).        TITLE OF CLASS OF SECURITIES:

                  Common Stock, par value $.0001 per share

ITEM 2(E).        CUSIP NUMBER

                  637184108

ITEM 3.           IF THIS  STATEMENT  IS  FILED  PURSUANT  TO RULE  13D-1(B), OR
                  13D-2(B) OR (C) , CHECK WHETHER THE PERSON FILING IS A:

                  (a)  [ ]  Broker or dealer registered under Section 15 of the
                            Exchange Act.

                  (b)  [ ]  Bank  as  defined  in  Section  3(a)  (6) of the
                            Exchange Act.

                  (c)  [ ]  Insurance company as defined in Section 3(a)(19) of
                            the Exchange Act.

                  (d)  [ ]  Investment company registered under Section 8 of the
                            Investment Company Act.

                  (e)  [ ]  An investment  adviser in accordance with Rule 13d-1
                            (b)(1) (ii) (E);

                  (f)  [ ]  An  employee  benefit  plan  or  endowment  fund  in
                            accordance with Rule 13d-1(b) (1) (ii) (F);

                  (g)  [ ]  A  parent  holding  company  or  control  person  in
                            accordance with Rule 13d-1(b) (1) (ii) (G);

                  (h)  [ ]  A savings  association  as defined in  Section 3 (b)
                            of the Federal Deposit

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                            Insurance Act.

                  (i)  [ ]  A church plan that is excluded  from the  definition
                            of an investment company under Section 3 (c) (14)of
                            the Investment Company Act.

                  (j)  [ ]  Group, in accordance  with Rule  13d-1(b)(1)(ii)(J).


ITEM 4.           OWNERSHIP.

                  Provide the  following  information  regarding  the  aggregate
number and percentage of the class of securities of the issue identified in Item
1.

                  (a) Amount Beneficially Owned:                   3,121,000

                  (b) Percent of Class:                                 7.1%

                  (c) Number of shares as to which such person has:

                        (i)   sole power to vote or to direct the vote:
                                                                   3,071,000

                        (ii)  shared power to vote or to direct vote:
                                                                      50,000 (1)

                        (iii) sole power to dispose or to direct the disposition
                              of:                                  3,071,000

                        (iv)  shared power to dispose or to direct the
                              disposition of:                         50,000 (1)
----------------
(1) Consists of shares owned by spouse.

ITEM 5.           OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

                  Not applicable.

ITEM 6.           OWNERSHIP OF  MORE  THAN  FIVE  PERCENT ON  BEHALF OF ANOTHER
                  PERSON.

                  Included  as shares for which there  exist  shared  voting and
                  dispositive  power are 50,000  shares  owned by Mr.  Haywood's
                  spouse,  which  spouse  would have the right to the receipt of
                  dividends from, and proceeds for the sale of, such shares.


ITEM 7.           IDENTIFICATION  AND  CLASSIFICATION  OF THE  SUBSIDIARY  WHICH
                  ACQUIRED  THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING
                  COMPANY OR CONTROL PERSON.

                  Not applicable.

ITEM 8.           IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

                  Not applicable.


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ITEM 9.           NOTICE OF DISSOLUTION OF GROUP.

                  Not applicable.

ITEM 10.          CERTIFICATION.

                  By signing  below I certify  that, to the best of my knowledge
and belief, the securities  referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing  the control of
the  issuer  of the  securities  and  were  not  acquired  and are  not  held in
connection  with or as a participant in any  transaction  having that purpose or
effect.


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                                    SIGNATURE

                  After  reasonable  inquiry and to the best of my knowledge and
belief,  I certify  that the  information  set forth in this  statement is true,
complete and correct.


                                                     APRIL 1, 2005
                                                     -------------
                                                        (Date)


                                                 /s/ GEORGE W. HAYWOOD
                                                 ----------------------
                                                      (Signature)


                                                     GEORGE W. HAYWOOD
                                                     -----------------
                                                       (Name/Title)



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