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FORM 8-K

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): March 5, 2002


AVI BioPharma, Inc.
(Exact name of registrant as specified in its charter)

Oregon
(State or other jurisdiction of
incorporation or organization)
  0-22613
(Commission File Number)
  93-0797222
(IRS Employer Identification Number)

One S.W. Columbia, Suite 1105
Portland, OR 97258
(Address of principal executive offices)

(503) 227-0554
Registrant's telephone number, including area code




Item 5. Other Events.

        AVI BioPharma, Inc. (the "Company") issued a press release on March 5, 2002, before the start of trading in its Common Stock on the Nasdaq National Market System, a copy of which is attached as Exhibit A.

        The Press Release announces that the Company has extended the final expiration date for exercise of two classes of its warrants to acquire shares of its Common Stock ($.0001 par value) ("Common Stock") by ninety-two (92) days. The warrants for which the expiration date has been extended are the following:

Item 7. Financial Statements, Pro Forma Financial Information and Exhibits.

        None


SIGNATURES

        Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Portland, State of Oregon, on March 5, 2002.

    AVI BIOPHARMA, INC.

 

 

By:

 

/s/  
ALAN P. TIMMINS      
Alan P. Timmins
President and Chief Operating Officer
(Principal Operating Officer)

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SIGNATURES

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EXHIBIT A

Text of Press Release

AVI Contacts:
AVI BioPharma Inc.
Denis R. Burger, Ph.D., CEO
Alan P. Timmins, President and COO
(503) 227-0554

Investor Contacts:
Lippert/Heilshorn & Associates Inc.
Bruce Voss (bvoss@lhai.com)
Jody Cain (jcain@lhai.com)
(310) 691-7100

Press Contacts:
Waggener Edstrom Bioscience
Colleen Beauregard (colleenb@wagged.com)
Andrew Fowler (andrewf@wagged.com)
(503) 443-7000

For Release 6 a.m. PST
March 5, 2002

AVI BioPharma to Extend Expiration Dates of AVIIW and AVIIZ Warrants

        PORTLAND, Ore.—March 5, 2002—AVI BioPharma Inc. (Nasdaq: AVII, AVIIW, AVIIZ) today announced that the company will extend, by three months each, the expiration dates of its warrants trading under the symbols AVIIW and AVIIZ. With the extension, AVIIW warrants will now expire on Sept. 3, 2002, and AVIIZ warrants will expire on Aug. 15, 2003.

        "The tragic global events of Sept. 11, 2001, removed about three months of equilibrium from the marketplace," said Denis R. Burger, Ph.D., AVI's chief executive officer. "AVI's directors agreed that this extension of time was appropriate and necessary in the interest of fairness to both our warrant holders and our shareholders."

        The AVIIW warrants originated in the company's initial public offering in 1997, and the AVIIZ warrants were part of the consideration in the company's purchase of ImmunoTherapy Corp. in 1998. The exercise price for each of the warrants remains unchanged at $13.50 per warrant for one share of common stock.

About AVI BioPharma

        AVI BioPharma develops therapeutic products for the treatment of life-threatening diseases using two technology platforms: NeuGene® antisense drugs and cancer immunotherapy. Its lead cancer agent, AVICINE®, a therapeutic cancer vaccine, has completed three Phase II trials in colorectal and pancreatic cancer and is in a Phase III pivotal trial in colorectal cancer. The first application of its NeuGene compounds, Resten-NG™, is designed to treat cancer, cardiovascular restenosis and other cell proliferation disorders by inhibiting the production of a cellular transcription factor, the oncogene c-myc. It is currently in Phase II trials for restenosis and in Phase I/II trials for cancer and polycystic kidney disease. More information about AVI is available on the Company's Web site at http://www.avibio.com/.

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        "Safe Harbor" Statement under the Private Securities Litigation Reform Act of 1995: The statements that are not historical facts contained in this release are forward-looking statements that involve risks and uncertainties, including, but not limited to, the results of research and development efforts, the results of preclinical and clinical testing, the effect of regulation by the FDA and other agencies, the impact of competitive products, product development, commercialization and technological difficulties, and other risks detailed in the Companies' Securities and Exchange Commission filings.

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EXHIBIT A Text of Press Release