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Agreement Expiration Date Agreement expiration date Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures Grant of restricted stock awards and vest of restricted stock units, net of cancellations Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures, Total Class of Stock [Domain] Class of Stock VYONDYS 53. V Y O N D Y S Fifty Three [Member] VYONDYS 53 [Member] Manufacturing-related deposits and prepaid expense current. Manufacturing Related Deposits And Prepaid Expense Current Manufacturing-related deposits and prepaids Fair Value Measurements, Recurring and Nonrecurring [Table Text Block] Assets and Liabilities Measured and Carried at Fair Value Cash deposits and money market funds. 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Amortization Of Discounts Premiums Investments Cash Equivalent And Short Term Investment Amortization of investment discount Billed Contracts Receivable Product sales receivable, net of discounts and allowances Revenues [Abstract] Revenues: Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Cancelled and forfeited Pompe license agreement. Pompe License Agreement [Member] Pompe License Agreement Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Abstract] Reconciliation of cash, cash equivalents and restricted cash: Goodwill and Intangible Assets Disclosure [Abstract] Contract with Customer, Liability Deferred Revenue Contract with Customer, Liability, Total Commitments and Contingencies Commitments and contingencies (Note 21) Rebates. 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Upfront Fee To Be Paid On Certain Achievement Payments to UWA on successful achievement of certain development and regulatory milestones Income Statement Location [Axis] Income Statement Location Investments [Domain] Investments Accrued Liabilities, Current Accrued expenses Total accrued expenses Increase (decrease) in additional paid in capital. 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Thermo Agreement [Member] Thermo Agreements [Member] Deferred Federal Income Tax Expense (Benefit) Federal Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Outstanding at end of year Taxes paid related to net share settlement of equity awards. Taxes Paid Related To Net Share Settlement Of Equity Awards Taxes paid related to net share settlement of equity awards Cash and Cash Equivalents [Line Items] Cash and Cash Equivalents [Line Items] Income tax (benefit) expense Income Tax Expense (Benefit) Total current provision Underwritten offering. 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F D A [Member] F D A Summary of reserves for discounts and allowances included in consolidated balance sheets. Summary Of Reserves For Discounts And Allowances Included In Consolidated Balance Sheets Table [Text Block] Summary of Total Reserves Included in Consolidated Balance Sheets Collaborative Arrangement and Arrangement Other than Collaborative [Table] Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Line of Credit Facility, Current Borrowing Capacity Current borrowing capacity Sale of Stock, Consideration Received on Transaction Proceeds received (in millions) Paragon Bioservices, Inc. 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Tranch B [Member] Tranch B [Member] Accumulated other comprehensive (loss) income, net of tax Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Cash and cash equivalents amortized cost basis. Cash And Cash Equivalents Amortized Cost Basis Cash and cash equivalents, Amortized cost Entity Address, Address Line One Entity Address, Address Line One Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value Aggregate intrinsic value of stock options exercised Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Grants outstanding at end of the period Grants outstanding at beginning of the period Fair Value, Liabilities Measured on Recurring and Nonrecurring Basis [Table Text Block] Summary of Fair Value of Level 3 Financial Liabilities Biopharma credit plc and biopharma credit investments V (Master) LP. 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[Member] Liabilities, Current Total current liabilities Less: accumulated amortization Finite-Lived Intangible Assets, Accumulated Amortization Less: accumulated amortization Development milestone and settlement upfront fee recognized as research and development expense. 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