101 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 103 - Statement - Consolidated Balance Sheets link:calculationLink link:presentationLink link:definitionLink 104 - Statement - Consolidated Balance Sheets (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 105 - Statement - Consolidated Statements of Operations and Comprehensive Loss link:calculationLink link:presentationLink link:definitionLink 106 - Statement - Consolidated Statements of Stockholders' Equity link:calculationLink link:presentationLink link:definitionLink 107 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:presentationLink link:definitionLink 108 - Disclosure - ORGANIZATION AND NATURE OF BUSINESS link:calculationLink link:presentationLink link:definitionLink 109 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES AND RECENT ACCOUNTING PRONOUNCEMENTS link:calculationLink link:presentationLink link:definitionLink 110 - Disclosure - SIGNIFICANT AGREEMENTS link:calculationLink link:presentationLink link:definitionLink 111 - Disclosure - FAIR VALUE MEASUREMENTS link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - CASH, CASH EQUIVALENTS AND SHORT-TERM INVESTMENTS link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - OTHER CURRENT ASSETS link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - PROPERTY AND EQUIPMENT link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - ACCRUED EXPENSES link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - WARRANTS link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - INDEBTEDNESS link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - EQUITY FINANCING link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - GOVERNMENT CONTRACTS link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - STOCK-BASED COMPENSATION link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - 401 (K) PLAN link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - RESTRUCTURING link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - INCOME TAXES link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - NET LOSS PER SHARE link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - COMMITMENTS AND CONTINGENCIES link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - FINANCIAL INFORMATION BY QUARTER (UNAUDITED) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES AND RECENT ACCOUNTING PRONOUNCEMENTS (Policies) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES AND RECENT ACCOUNTING PRONOUNCEMENTS (Tables) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - FAIR VALUE MEASUREMENTS (Tables) link:calculationLink link:presentationLink link:definitionLink 130 - Disclosure - CASH, CASH EQUIVALENTS AND SHORT-TERM INVESTMENTS (Tables) link:calculationLink link:presentationLink link:definitionLink 131 - Disclosure - OTHER CURRENT ASSETS (Tables) link:calculationLink link:presentationLink link:definitionLink 132 - Disclosure - PROPERTY AND EQUIPMENT (Tables) link:calculationLink link:presentationLink link:definitionLink 133 - Disclosure - ACCRUED EXPENSES (Tables) link:calculationLink link:presentationLink link:definitionLink 134 - Disclosure - WARRANTS (Tables) link:calculationLink link:presentationLink link:definitionLink 135 - Disclosure - INDEBTEDNESS (Tables) link:calculationLink link:presentationLink link:definitionLink 136 - Disclosure - GOVERNMENT CONTRACTS (Tables) link:calculationLink link:presentationLink link:definitionLink 137 - Disclosure - STOCK-BASED COMPENSATION (Tables) link:calculationLink link:presentationLink link:definitionLink 138 - Disclosure - RESTRUCTURING (Tables) link:calculationLink link:presentationLink link:definitionLink 139 - Disclosure - INCOME TAXES (Tables) link:calculationLink link:presentationLink link:definitionLink 140 - Disclosure - NET LOSS PER SHARE (Tables) link:calculationLink link:presentationLink link:definitionLink 141 - Disclosure - COMMITMENTS AND CONTINGENCIES (Tables) link:calculationLink link:presentationLink link:definitionLink 142 - Disclosure - FINANCIAL INFORMATION BY QUARTER (UNAUDITED) (Tables) link:calculationLink link:presentationLink link:definitionLink 143 - Disclosure - Organization and Nature of Business - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 144 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 145 - Disclosure - Summary of Estimated Useful Lives of Plant and Equipment (Detail) link:calculationLink link:presentationLink link:definitionLink 146 - Disclosure - Summary of Estimated Future Amortization for Patent Costs (Detail) link:calculationLink link:presentationLink link:definitionLink 147 - Disclosure - Significant Agreements - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 148 - Disclosure - Assets and Liabilities Measured and Carried at Fair Value (Detail) link:calculationLink link:presentationLink link:definitionLink 149 - Disclosure - Summary of Company Cash, Cash Equivalents and Short-term Investments (Detail) link:calculationLink link:presentationLink link:definitionLink 150 - Disclosure - Summary of Other Current Assets (Detail) link:calculationLink link:presentationLink link:definitionLink 151 - Disclosure - Summarizes Components of Property and Equipment, Net (Detail) link:calculationLink link:presentationLink link:definitionLink 152 - Disclosure - Property and Equipment - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 153 - Disclosure - Summary of Accrued Expenses (Detail) link:calculationLink link:presentationLink link:definitionLink 154 - Disclosure - Warrants - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 155 - Disclosure - Reconciliation of Change in Value of Company's Warrants Liability (Detail) link:calculationLink link:presentationLink link:definitionLink 156 - Disclosure - Summary of Warrant Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 157 - Disclosure - Indebtedness - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 158 - Disclosure - Indebtedness - Summarizes Total Payments under Company's Debt Arrangements (Detail) link:calculationLink link:presentationLink link:definitionLink 159 - Disclosure - Equity Financing - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 160 - Disclosure - Revenue from United States Government Contracts and Other Revenue (Detail) link:calculationLink link:presentationLink link:definitionLink 161 - Disclosure - Government Contracts - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 162 - Disclosure - Stock Based Compensation - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 163 - Disclosure - Assumptions for Measuring Fair Values of Stocks (Detail) link:calculationLink link:presentationLink link:definitionLink 164 - Disclosure - Assumptions for Measuring Fair Values of Stocks (Parenthetical) (Detail) link:calculationLink link:presentationLink link:definitionLink 165 - Disclosure - Summary of Stock Option Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 166 - Disclosure - Summary of Company's Stock Options Vested and Exercised (Detail) link:calculationLink link:presentationLink link:definitionLink 167 - Disclosure - Summary of Restricted Stock Award Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 168 - Disclosure - Summary of Restricted Stock Unit Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 169 - Disclosure - Summary of Stock Appreciation Rights Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 170 - Disclosure - Summary of Stock-Based Compensation Expense by Function Included within Consolidated Statement of Operations and Comprehensive Loss (Detail) link:calculationLink link:presentationLink link:definitionLink 171 - Disclosure - Summary of Stock-Based Compensation Expense by Grant Type Included within Consolidated Statement of Operations and Comprehensive Loss (Detail) link:calculationLink link:presentationLink link:definitionLink 172 - Disclosure - 401 (K) PLAN - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 173 - Disclosure - Restructuring - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 174 - Disclosure - Restructuring - Changes in Liability and Balance Related to Restructuring Plans (Detail) link:calculationLink link:presentationLink link:definitionLink 175 - Disclosure - Restructuring - Summarizes Restructuring Expense (Detail) link:calculationLink link:presentationLink link:definitionLink 176 - Disclosure - Income Taxes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 177 - Disclosure - Analysis of Deferred Tax Assets (Liabilities) (Detail) link:calculationLink link:presentationLink link:definitionLink 178 - Disclosure - Reconciliation Between Effective Tax Rate and Income Tax Rate (Detail) link:calculationLink link:presentationLink link:definitionLink 179 - Disclosure - Basic and Diluted Net Loss Per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 180 - Disclosure - Basic and Diluted Net Loss Per Share (Parenthetical) (Detail) link:calculationLink link:presentationLink link:definitionLink 181 - Disclosure - Commitments and Contingencies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 182 - Disclosure - Summary of Aggregate Non-Cancelable Future Minimum Payments under Company's Leases (Detail) link:calculationLink link:presentationLink link:definitionLink 183 - Disclosure - Non-Cancelable Contractual Obligations (Detail) link:calculationLink link:presentationLink link:definitionLink 184 - Disclosure - Financial Information by Quarter (Detail) link:calculationLink link:presentationLink link:definitionLink